In the eyes of the City, where the form-based codes have been established, the answer is no. The boundaries of the form-based code area are approximately the FWWR railroad on the west (this eliminates Mistletoe Heights and Midtown), the Union Pacific Railroad on the north, the BNSF Railway on the east, and a variable boundary on the south that goes along Allen Ave., Travis Ave., the southern property line of all of Magnolia, Hurley Ave. and the alley between Hurley & 8th, then down to W. Arlington, then 1/2 block west to the railroad. Cook Children's Hospital properties are a donut in this area and the zoning jumps across the BNSF tracks to include the area around I-35W.
I think the Near Southside's business development boundaries extend a little further out than the form-based code areas.